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Serotonin N-acetyl transferase molecule

Serotonin N-acetyl transferase molecule


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Serotonin N-acetyl transferase molecule

Serotonin N-acetyl transferase molecule. Computer model showing the molecular structure of the four sequence motifs (coloured) that make up the arylalkylamine N-acetyltransferase (aNAT) complex. aNAT is the penultimate enzyme involved in the conversion of serotonin to melatonin in the cells of the pineal gland in the brain. Melatonin modulates the function of the circadian clock, influencing activity and sleep. aNAT is rapidly inactivated when animals are exposed to light at night and therefore controls the night/day rhythm of melatonin production

Science Photo Library features Science and Medical images including photos and illustrations

Media ID 6303309

© LAGUNA DESIGN/SCIENCE PHOTO LIBRARY

Activity Circadian Clock Control Endocrine System Enzyme Hormonal Hormone Hormones Pineal Gland Proteins Regulation Rhythm Sleep Structural Transferase Bio Chemistry Biochemical Molecular Model Motif Motifs Protein Rhythms


EDITORS COMMENTS
This print showcases the intricate molecular structure of the serotonin N-acetyl transferase (aNAT) molecule. The computer-generated model vividly highlights the four sequence motifs, each represented by a distinct color, that compose the complex aNAT enzyme. Found in the cells of the pineal gland within our brain, aNAT plays a crucial role as the penultimate enzyme in converting serotonin to melatonin. Melatonin, known for its influence on our circadian rhythm and sleep patterns, is modulated by this remarkable protein. As depicted in this stunning artwork, aNAT's activity is rapidly inhibited when exposed to light at night. Consequently, it governs the delicate balance between day and night rhythms of melatonin production. The structural elegance portrayed here not only emphasizes its biological significance but also serves as an artistic representation of biochemistry at work. This image beautifully captures how proteins regulate essential hormonal processes within our body. With its scientific precision and aesthetic appeal, this photograph offers an intriguing glimpse into the world of molecular biology and chemistry. It reminds us of both nature's complexity and beauty while shedding light on one aspect of our endocrine system's functionality – specifically how it controls sleep-wake cycles through melatonin modulation. Science Photo Library has once again provided us with an exceptional visual exploration into cutting-edge research that lies at the intersection of art and science.

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