Coagulation factor complex molecule C014 / 0626
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Coagulation factor complex molecule C014 / 0626
Coagulation factor complex molecule. Molecular model showing a blood clotting factor VIIa-tissue factor complex molecule (blue and white ribbons) with a tissue factor pathway inhibitor (TFPI, spheres top right) molecule bound. Tissue factor, also known as factor III, is found on the outside of blood vessels. When the vessel is injured it comes into contact with factor VII (FVII) circulating in the blood stream. They bind together, activating FVII as apart of the coagulation cascade, the physiological process that leads to blood clotting in the case of injury. Molecules further down the cascade activate TFPI, suppressing the cascade
Science Photo Library features Science and Medical images including photos and illustrations
Media ID 9214603
© RAMON ANDRADE 3DCIENCIA/SCIENCE PHOTO LIBRARY
Coagulation Complex Compound Enzyme Inhibition Negative Feedback Secondary Structure Serine Protease Biochemical Biochemistry Molecular Molecular Model Protein
EDITORS COMMENTS
This print showcases the intricate molecular structure of the coagulation factor complex molecule C014 / 0626. The blue and white ribbons elegantly represent the blood clotting factor VIIa-tissue factor complex molecule, while a spherical representation of the tissue factor pathway inhibitor (TFPI) is bound at the top right corner. Tissue factor, also known as factor III, resides on the outer surface of blood vessels. In case of injury to these vessels, it interacts with circulating factor VII (FVII) present in our bloodstream. This interaction triggers their binding and subsequently activates FVII as part of the coagulation cascade - a vital physiological process leading to blood clot formation. Further down this cascade, molecules activate TFPI which acts as a suppressor for this intricate mechanism. The artwork beautifully portrays how TFPI binds to regulate and inhibit excessive clotting. The image not only highlights the complexity but also emphasizes its significance in maintaining hemostasis within our bodies. It serves as a visual reminder that even at such microscopic levels, there are remarkable biochemical processes occurring constantly to ensure our well-being. Ramon Andrade's masterful illustration captures both scientific accuracy and artistic beauty, making it an invaluable addition for anyone interested in biology or biochemistry.
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